Wastewater epidemiology can guide local clinical decisions about circulating viruses

The findings of a new study posted to the medRxiv* preprint server depicted that wastewater-based epidemiology (WBE) can provide information about the circulating respiratory viruses in a community. This method not only saves time and money, but can also aid in appropriate clinical decision-making, behavioral change, and public health interventions. Research: Wastewater monitoring of human … Read more

Food, vaccines, bacteria and viruses can all prepare our immune system to attack SARS-CoV-2

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the ongoing coronavirus disease pandemic 2019 (COVID-19), mainly causes mild to moderate upper respiratory tract disease. However, some individuals with COVID-19 develop serious infections and require hospitalization. Study: reaction of SARS-CoV-2 antibodies with other pathogens, vaccines and food antigens. Image Credit: Peddalanka Ramesh Babu / … Read more

Differences in protection against previous infection or vaccination against infection with Omicron BA.4/5 or BA.2

In a recent study posted to the medRxiv* preprint server, researchers examined the differences in vaccination- and prior infection-induced immunities against the Omicron BA.2 and BA.4/5 subvariants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: Higher risk of SARS-CoV-2 Omicron BA.4/5 infection than BA.2 infection after previous BA.1 infection, The Netherlands, May 2 to … Read more

Rational treatment strategies for SARS-CoV-2 derived from human pluripotent stem cell models

In a recent study posted to the bioRxiv* preprint server, researchers in Australia investigated the molecular mechanisms of the pulmonary and cardiac complications caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using human stem cell-derived heart and lung cells. Study: Parallel use of pluripotent lung and heart models of human stem cells … Read more

First data on the Omicron BA.4/5 combination vaccine from Pfizer-BioNTech

In a recent study posted to the bioRxiv* preprint server, researchers from Germany and the United States analyzed the association between exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.4/BA.5 spike glycoprotein and pan-Omicron neutralization. Study: Exposure to BA.4/BA.5 Spike glycoprotein stimulates pan-Omicron neutralization in vaccine-experienced humans and mice. Image Credit: Naeblys/Shutterstock Background … Read more

Researchers examine neurological manifestations in tall COVID patients

In a recent study published in naturopathyresearchers assessed the long-term neurological consequences in the post-acute phase of coronavirus disease 2019 (COVID-19) or long-term COVD. Study: Long-term neurological outcomes of COVID-19. Image Credit: Starocean/Shutterstock Long COVID-19 refers to the spectrum of post-acute COVID-19 consequences with various extrapulmonary manifestations, including neurological abnormalities. Most studies of long-term COVID-associated … Read more

Population-wide cohort study detects increase in major arterial and venous thrombotic events immediately after COVID-19 diagnosis

In a recent study published in CirculationResearchers examined the link between coronavirus disease 2019 (COVID-19) and vascular thrombotic events using a population-wide cohort study in England and Wales. Study: Association of COVID-19 with severe arterial and venous thrombotic disease: a population-wide cohort study of 48 million adults in England and Wales. Image credit: MattLphotography/Shutterstock Background … Read more

Researchers report development of self-assembled trimeric RBD subunit vaccine that can prevent SARS-CoV-2 infection

Since the emergence of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19) pandemic, several genomic mutations have been detected. For example, the currently dominantly circulating SARS-CoV-2 Omicron variant contains many mutations responsible for its increased virulence and transmissibility compared to the original SARS-CoV-2 strain. Study: A proprietary … Read more

Clinical and epidemiological features of SARS-CoV-2 in companion animals

In a recent study posted to the Research Square* preprint server, researchers examined the clinical and epidemiological features of coronavirus disease 2019 (COVID-19) in dogs and cats. Numerous beneficial effects of pet ownership, including mental health benefits, have been scientifically established. Companion animals account for 60% of all animals reported to the World Organization for … Read more

Needle-free jet injection of new COVID-19 DNA vaccine shows promise in animal model

In a recent study posted to the bioRxiv*server, researchers from the United States Army Medical Research Institute of Infectious Diseases evaluated the immunogenicity of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) deoxyribonucleic acid (DNA) vaccine, nCOV-S(JET), in rhesus monkeys. A previous evaluation of this coronavirus disease 2019 (COVID-19) DNA vaccine targeting the SARS-CoV-2 spike … Read more